I briefly used Box.net as a virtual 1GB memory stick. Briefly because after the initial transfer of important files, the onus was on me to identify files I had changed recently and upload them.
Mozy seems better suited to lazy people. You simply download a lightweight client, identify folders you want mirrored and Mozy encrypts and mirrors them, quietly in the background.
When you add new files, Mozy mirrors the incremental changes. Mozy offers 2GB of storage for free.
Also, Mozy includes the phrase ‘Reticulating splines’ during initialisation.